Fostering open collaboration in drug development for paediatric brain tumours

Paediatric brain tumours.

Brain tumours constitute the most frequent solid tumour in childhood. At approximately 20% of paediatric malignant disease they remain uncommon with incidence of 2-3 per 100,000. Glial tumours represent over half of brain tumours in children, although in comparison with adult gliomas, where high grade tumours predominate, low grade tumours are more frequent. These characteristically include cys...

Open Source Collaboration for Fostering Off-The-Shelf Components Selection

The use of Off-The-Shelf software components in ComponentBased Development implies many challenges. One of them is the lack of available and well-suited data to support selection of suitable OTS components. This paper proposes a feasible and incremental way to federate and reuse the different efforts for finding, selecting, and maintaining OTS components in a structured way. This is done not on...

Highlights of Children with Cancer UK’s Workshop on Drug Delivery in Paediatric Brain Tumours

The first Workshop on Drug Delivery in Paediatric Brain Tumours was hosted in London by the charity Children with Cancer UK. The goals of the workshop were to break down the barriers to treating central nervous system (CNS) tumours in children, leading to new collaborations and further innovations in this under-represented and emotive field. These barriers include the physical delivery challeng...

Genetic Instability in Paediatric and Adult Brain Tumours

Fostering Canadian drug research and development for neglected tropical diseases

Patricia Gabriel, MD, is a family medicine resident at St. Paul’s Hospital, Vancouver, BC, Canada. Rebecca Goulding, PhD, is a postdoctoral fellow at the ISIS Research Centre, Sauder School of Business, University of British Columbia, Vancouver. Cecily Morgan-Jonker, BSc, is a medical student at the University of British Columbia. Shannon Turvey, MSc, is a medical student at the University of B...